The section of Child & Adolescent Psychiatry at the MRC Centre are currently investigating Attention Deficit Hyperactivity Disorder (ADHD). Translational work on Attention-Deficit Hyperactivity Disorder (ADHD) at the Centre has focused on examining the wide spectrum of severity and features of this disorder and exploring the ways in which this relates to genetic, cognitive, and social risk mechanisms.
The Centre's work is also beginning to examine in more detail an important (both clinically and socially) sub-group of patients. They are examining a group of patients with antisocial behaviour (ASB) and ADHD using cognitive and imaging studies to investigate the underlying mechanisms that mediate links between their clinical and genetic features. Here, Professor Anita Thepar of the MRC centre talks to BBC news about their recent research into ADHD. As explained in their research paper found in The Lancet: ‘findings provide genetic evidence of an increased rate of rare chromosomal deletions and duplications called Copy Number Variants in individuals with ADHD and suggest that ADHD is not purely a social construct’.